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Dendrimers with N , N -Disubstituted Hydrazines as End Groups, Useful Precursors for the Synthesis of Water-Soluble Dendrimers Capped with Carbohydrate, Carboxylic or Boronic Acid Derivatives

Identifieur interne : 003749 ( Main/Exploration ); précédent : 003748; suivant : 003750

Dendrimers with N , N -Disubstituted Hydrazines as End Groups, Useful Precursors for the Synthesis of Water-Soluble Dendrimers Capped with Carbohydrate, Carboxylic or Boronic Acid Derivatives

Auteurs : Rosa-Mar A Sebastián [France] ; Germinal Magro [France] ; Anne-Marie Caminade [France] ; Jean-Pierre Majoral [France]

Source :

RBID : ISTEX:EDF882626DF18B37E6B3F9B8989D739BBFF7D1B7

English descriptors

Abstract

Abstract: The first synthesis of dendrimers possessing N,N-disubstituted hydrazines as end groups allows us to carry out a versatile reactivity. Carbohydrate, carboxylic acid and boronic acid derivatives have been linked to the surface of the dendrimer in a very simple fashion, using the Schiff condensation. The stability of the resulting functionalized dendrimers has been checked: those linked to carboxylic acid derivatives are stable more than 7months in water, demonstrating the high stability of both the hydrazone bonds and the whole skeleton of the dendrimer.

Url:
DOI: 10.1016/S0040-4020(00)00576-7


Affiliations:


Links toward previous steps (curation, corpus...)


Le document en format XML

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